The analysis of immunostimulants assortment on the Ukrainian pharmaceutical market
DOI:
https://doi.org/10.24959/uekj.19.31Keywords:
immunostimulants, interferon, pharmaceutical market of Ukraine, dosage form, candidiasisAbstract
Today there is a question of searching for prospective methods of candidiasis therapy aimed at immunity stimulating and restoring the qualitative and quantitative composition of women’s microflora.
Aim. To make an analysis of immunostimulants on the Ukrainian pharmaceutical market.
Materials and methods. The immunostimulants assortment was analyzed using the classification of ATS according to the State Register of Medicines of Ukraine, October 2019.
Results. The marketing analysis presents the classification, mechanism of drug effect, countries of manufacture, types of dosage forms for immunostimulants. According to the classification of ATS L03A «Immunostimulants», it was determined that it consists of several subgroups, namely: L03A A – colony-stimulating factors, 12 drugs (9.76 %); L03A B – interferon preparations, 61 drugs (49.59 %); L03A C – interleukin preparations, 0 drugs; L03A X – other immunostimulants; 50 drugs (40.65 %). According to the results obtained, countries manufacturing immunostimulants, it was found that the main countries importing immunostimulants are: USA 5,83 %, Israel 4,50 %, Slovenia and Switzerland 3,85 % each, Germany 3,21 %. Ukrainian manufacturers supply 69.03 % of immunostimulants of the total. According to the analysis of dosage forms presented on the pharmaceutical market in Ukraine, it was found that immunostimulants are represented by types of dosage forms. The main ones are injection solution 35,03 %, lyophilized injection powder 30,57 %, suppositories 10,83 %, tincture for oral use 5,73 %, oral drops 2.55 %, syrup 1.91 %.
Conclusions. The analysis of immunostimulating drugs assortment on the pharmaceutical market in Ukraine showed that dosage form of suppositories is widespread enough. And suppositories containing interferon in combination with other drugs, that is, complex effect, are not represented at all. Therefore, it is relevant to develop the composition and technology of a new domestic combined drug in the form of suppositories based on immunostimulant, antifungal drugs and probiotics for the treatment of candidiasis.
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