Study of negative outcomes in the results of using medicines by patients in Ukraine and abroad
DOI:
https://doi.org/10.24959/uekj.19.14Keywords:
medicine safety, adverse drug reaction, medication error, pharmacovigilanceAbstract
The rapid development of the pharmaceutical industry, the emergence of new forms of drug advertising, modern sales technologies, self-treatment are of concern. At the same time, there are tendencies in the case of the prescribing or dispensation medicines, as well as mistakes in taking the drugs by patients. This leads to patients health harm, and in some cases leads to lethal effects and additional funds.
Aim. To study the negative effects of using medicines by patients inUkraine and abroad.
Results. The analysis of definitions related to drugs safety, the classification of medication-related errors, the relationship of medication errors with adverse reactions of drug. The analysis of current state functioning efficiency of the pharmaceutical supervision system inUkraine has been carried out, according to the results of which it is established that domestic system meets the recommendations of the World Health Organization, however, today does not take into account all developed European recommendations.
Conclusions. It is established that in the world today there is no single unified classification of medication related errors. It is determined that the most common defining characteristic of mistakes during pharmacotherapy is the term "medication error". Taking into account the general tendencies, the following categories of errors are distinguished: mistakes occurred in a case of drug administration, use of medicines if inpatient treatment, and when giving a drug to a pharmaceutical worker. It has been determined that systems of pharmaceutical supervision of many countries acknowledging the data of medication error. The domestic pharmacovigilance system as a whole complies with international standards, but still does not take into account all developed recommendations and needs to be reformed, in view of Eurointegration processes taking place inUkraine.
References
Lebega, O., Nwokike, J., and Walkowiak, H. (2012.) Safety of Medicinal Products in Ukraine: Assessment of the Pharmacovigilance System and its Performance. Submitted to theU.S. Agency for International Development by the Strengthening Pharmaceutical Systems (SPS) Program.Arlington,VA: Management Sciences for Health.
Kotvitska, A., Surikova, I., & Gavrish, N. (2015). The study of introduction of the ethics code of pharmacists of Ukrainein to the practical activity. Socìal’na farmacìâ v ohoronì zdorov'â, 1(1), 45–52. https://doi.org/10.24959/sphhcj.15.7
Matvieieva, O. V., Zimenkovskyi, A. B., Yaichenia, V. P. (2012). Ratsionalna farmakoterapiia, 4 (25), 5–10.
Zimenkovskyi, A. B., Ryvak, T. B., Khanyk, N. L. (2011). Klinichna farmatsiia, farmakoterapiia ta medychna standartyzatsiia,1-2, 23–31.
Ofitsiinyi sait Derzhavnoho Ekspertnoho Tsentru Ministerstva okhorony zdorov’ia Ukrainy. (n.d.). Ofitsiinyi sait. Available at: http://www.dec.gov.ua/
Zakon Ukrainy «Pro zatverdzhennia Poriadku zdiisnennia nahliadu za pobichnymy reaktsiiamy likarskykh zasobiv, dozvolenykh do medychnoho zastosuvannia» №898 vid 27.12.2006 r. (2006). Available at: https://www.rada.gov.ua
Aronson, J. K. (2009). Medication errors: definitions and classification. British Journal of Clinical Pharmacology, 67(6), 599–604. https://doi.org/10.1111/j.1365-2125.2009.03415.x
Karthikeyan, M., Balasubramanian, T., Mohammed Ibrahim Khaleel, Muhammed Sahl and Rashifa, P. (2015). A Systematic Review on Medication Errors. International Journal of Drug Development and Research, 7(4), 9–11.
Williams, D. (2007). Medication Errors. The Journal of the Royal College of Physicians of Edinburgh, 34 (4), 343–346.
Ofitsiinyi sait Natsionalnoi koordynatsiinoi rady SShA shchodo raportuvannia ta poperedzhennia likopov’iazanykh pomylok. (n.d.). Available at: http://www.nccmerp.org/
Ofitsiinyi sait Upravlinnia prodovolstva i medykamentiv. (n.d.). Available at: http://www.fda.gov/
Nakaz MOZ Ukrainy «Nastanova Likarski zasoby. Nalezhni praktyky farmakonahliadu» № 299 vid 21.05.2015. (2015). Available at: http://www.rada.gov.ua/
Downloads
Published
Issue
Section
License
Copyright (c) 2019 National University of Pharmacy
This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors who publish with this journal agree to the following terms:- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).
