Development and validation of method of control related substances in the substances 4­oxo­2­thioxo­1,4­dihydrothieno[3,2­d]pyrimidin­3­propanoic acid

Authors

  • O. V. Tkachenko National University of Pharmacy, Ukraine
  • S. M. Gubar National University of Pharmacy, Ukraine

DOI:

https://doi.org/10.24959/uekj.16.41

Keywords:

thieno[3, 2- d ]pyrimidine, HPLC, validation

Abstract

A HPLC method for related substances of and 4-oxo-2-thioxo-1,4-dihydrothieno[3,2-d]pyrimidin-3-propanoic acid determination was developed. The impurities of newly synthesized derivative of thieno[3,2-d]pyrimidine chromatographic profile was studied using reversedphase HPLC. The created HPLC methodic was validated.

References

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Published

2016-11-23

Issue

No. 4(48) (2016)

Section

Quality, standardization and certification in pharmacy

License

Copyright (c) 2016 National University of Pharmacy

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